Anti-Factor XIIIa antibody [4E4-3A8-10G2] (STJA0033519)

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STJA0033519
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Factor XIIIa for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 4E4-3A8-10G2
Conjugation: Unconjugated
Isotype: IgG3
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification: Affinity Chromatography
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:500
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: F13A1
Gene ID: 2162
Uniprot ID: F13A_HUMAN
Immunogen: Synthesized peptide derived from human Factor XIIIa
Post Translational Modifications The activation peptide is released by thrombin.
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Protein Name Coagulation Factor Xiii A Chain
Coagulation Factor Xiiia
Protein-Glutamine Gamma-Glutamyltransferase A Chain
Transglutaminase A Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140875
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Secreted
Secreted Into The Blood Plasma
Cytoplasmic In Most Tissues
But Also Secreted In The Blood Plasma
Alternative Antibody Names Anti-Coagulation Factor Xiii A Chain antibody
Anti-Coagulation Factor Xiiia antibody
Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody
Anti-Transglutaminase A Chain antibody
Anti-F13A1 antibody
Anti-F13A antibody

Information sourced from Uniprot.org

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