Anti-FABP5 antibody (40-120 aa) (STJ192489)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 40-120
General Information
| Short Description | Rabbit polyclonal anti-Fatty acid-binding protein 5 (40-120 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FABP5 |
| Gene ID | 2171 |
| Uniprot ID | FABP5_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 40-120 |
| Immunogen Region | 40-120 aa |
| Specificity | FABP5 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta.which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation. May be involved in keratinocyte differentiation. |
| Protein Name | Fatty Acid-Binding Protein 5Epidermal-Type Fatty Acid-Binding ProteinE-FabpFatty Acid-Binding Protein - EpidermalPsoriasis-Associated Fatty Acid-Binding Protein HomologPa-Fabp |
| Database Links | Reactome: R-HSA-163560Reactome: R-HSA-5362517Reactome: R-HSA-6798695Reactome: R-HSA-9725554 |
| Cellular Localisation | CytoplasmNucleusSynapsePostsynaptic DensitySecretedLocalizes Primarily To The CytoplasmUpon Certain Ligand BindingA Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into NucleusSecreted By AstrocytesBut Not By Neurons |
| Alternative Antibody Names | Anti-Fatty Acid-Binding Protein 5 antibodyAnti-Epidermal-Type Fatty Acid-Binding Protein antibodyAnti-E-Fabp antibodyAnti-Fatty Acid-Binding Protein - Epidermal antibodyAnti-Psoriasis-Associated Fatty Acid-Binding Protein Homolog antibodyAnti-Pa-Fabp antibodyAnti-FABP5 antibody |
Information sourced from Uniprot.org