| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Fatty acid-binding protein 5 (40-120 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FABP5 |
| Gene ID: | 2171 |
| Uniprot ID: | FABP5_HUMAN |
| Immunogen Region: | 40-120 aa |
| Specificity: | FABP5 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 40-120 |
| Function | Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta.which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation. May be involved in keratinocyte differentiation. |
| Protein Name | Fatty Acid-Binding Protein 5 Epidermal-Type Fatty Acid-Binding Protein E-Fabp Fatty Acid-Binding Protein - Epidermal Psoriasis-Associated Fatty Acid-Binding Protein Homolog Pa-Fabp |
| Database Links | Reactome: R-HSA-163560 Reactome: R-HSA-5362517 Reactome: R-HSA-6798695 Reactome: R-HSA-9725554 |
| Cellular Localisation | Cytoplasm Nucleus Synapse Postsynaptic Density Secreted Localizes Primarily To The Cytoplasm Upon Certain Ligand Binding A Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into Nucleus Secreted By Astrocytes But Not By Neurons |
| Alternative Antibody Names | Anti-Fatty Acid-Binding Protein 5 antibody Anti-Epidermal-Type Fatty Acid-Binding Protein antibody Anti-E-Fabp antibody Anti-Fatty Acid-Binding Protein - Epidermal antibody Anti-Psoriasis-Associated Fatty Acid-Binding Protein Homolog antibody Anti-Pa-Fabp antibody Anti-FABP5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
