Anti-F2RL2 antibody (150-250 aa) (STJ11106749)

SKU:
STJ11106749
€140.63 - €655.63
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: F2RL2
Gene ID: 2151
Uniprot ID: PAR3_HUMAN
Immunogen Region: 150-250 aa
Specificity: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human F2RL2 (NP_004092.1).
Immunogen Sequence: IAYHLNGNNWVFGEVLCRAT TVIFYGNMYCSILLLACISI NRYLAIVHPFTYRGLPKHTY ALVTCGLVWATVFLYMLPFF ILKQEYYLVQPDITTCHDVH N
Tissue Specificity Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
Post Translational Modifications A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
Function Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Protein Name Proteinase-Activated Receptor 3
Par-3
Coagulation Factor Ii Receptor-Like 2
Thrombin Receptor-Like 2
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-456926
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Proteinase-Activated Receptor 3 antibody
Anti-Par-3 antibody
Anti-Coagulation Factor Ii Receptor-Like 2 antibody
Anti-Thrombin Receptor-Like 2 antibody
Anti-F2RL2 antibody
Anti-PAR3 antibody

Information sourced from Uniprot.org