Tissue Specificity | Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. |
Post Translational Modifications | A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. |
Function | Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. |
Protein Name | Proteinase-Activated Receptor 3Par-3Coagulation Factor Ii Receptor-Like 2Thrombin Receptor-Like 2 |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-456926 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Proteinase-Activated Receptor 3 antibodyAnti-Par-3 antibodyAnti-Coagulation Factor Ii Receptor-Like 2 antibodyAnti-Thrombin Receptor-Like 2 antibodyAnti-F2RL2 antibodyAnti-PAR3 antibody |
Information sourced from Uniprot.org