Anti-F13A1 antibody (1-50) {Biotin} (STJ501103)

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STJ501103-100
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Cat/Human/Monkey/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-F13A1 (1-50) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Biotin
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.55-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: F13A1
Gene ID: 2162
Uniprot ID: F13A_HUMAN
Immunogen Region: 1-50
Immunogen: Synthetic peptide taken within amino acid region 1-50 on human factor XIII A subunit protein.
Post Translational Modifications The activation peptide is released by thrombin.
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Protein Name Coagulation Factor Xiii A Chain
Coagulation Factor Xiiia
Protein-Glutamine Gamma-Glutamyltransferase A Chain
Transglutaminase A Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140875
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Secreted
Secreted Into The Blood Plasma
Cytoplasmic In Most Tissues
But Also Secreted In The Blood Plasma
Alternative Antibody Names Anti-Coagulation Factor Xiii A Chain antibody
Anti-Coagulation Factor Xiiia antibody
Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody
Anti-Transglutaminase A Chain antibody
Anti-F13A1 antibody
Anti-F13A antibody

Information sourced from Uniprot.org

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