Anti-F13A1 antibody (1-220 aa) (STJ11106253)

SKU:
STJ11106253
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: F13A1
Gene ID: 2162
Uniprot ID: F13A_HUMAN
Immunogen Region: 1-220 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human F13A1 (NP_000120.2).
Immunogen Sequence: MSETSRTAFGGRRAVPPNNS NAAEDDLPTVELQGVVPRGV NLQEFLNVTSVHLFKERWDT NKVDHHTDKYENNKLIVRRG QSFYVQIDFSRPYDPRRDLF RVEYVIGRYPQENKGTYIPV PIVSELQSGKWGAKIVMRED RSVRLSIQSSPKCIVGKFRM YVAVWTPYGVLRTSRNPETD TYILFNPWCEDDAVYLDNEK EREEYVLNDIGVIFYGEVND
Post Translational Modifications The activation peptide is released by thrombin.
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Protein Name Coagulation Factor Xiii A Chain
Coagulation Factor Xiiia
Protein-Glutamine Gamma-Glutamyltransferase A Chain
Transglutaminase A Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140875
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Secreted
Secreted Into The Blood Plasma
Cytoplasmic In Most Tissues
But Also Secreted In The Blood Plasma
Alternative Antibody Names Anti-Coagulation Factor Xiii A Chain antibody
Anti-Coagulation Factor Xiiia antibody
Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody
Anti-Transglutaminase A Chain antibody
Anti-F13A1 antibody
Anti-F13A antibody

Information sourced from Uniprot.org

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