Anti-EXTL2 antibody (141-191 aa) (STJ194954)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human EXTL2 at the amino acid range 141-191
General Information
| Short Description | Rabbit polyclonal anti-Exostosin-like 2 (141-191 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EXTL2 |
| Gene ID | 2135 |
| Uniprot ID | EXTL2_HUMAN |
| Immunogen | Synthesized peptide derived from the human EXTL2 at the amino acid range 141-191 |
| Immunogen Region | 141-191 aa |
| Specificity | This antibody detects endogenous levels of EXTL2 at Human/Mouse |
Additional Info
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. |
| Protein Name | Exostosin-Like 2Alpha-1 -4-N-Acetylhexosaminyltransferase Extl2Alpha-Galnact Extl2Ext-Related Protein 2Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Cleaved Into - Processed Exostosin-Like 2 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinProcessed Exostosin-Like 2: SecretedA Soluble Form Is Found In The Serum |
| Alternative Antibody Names | Anti-Exostosin-Like 2 antibodyAnti-Alpha-1 -4-N-Acetylhexosaminyltransferase Extl2 antibodyAnti-Alpha-Galnact Extl2 antibodyAnti-Ext-Related Protein 2 antibodyAnti-Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Cleaved Into - Processed Exostosin-Like 2 antibodyAnti-EXTL2 antibodyAnti-EXTR2 antibody |
Information sourced from Uniprot.org