| Short Description : | Goat polyclonal EWSR1 (N-Term) antibody for use in WB in human, rat, mouse, canine and monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Goat |
| Reactivity: | Human/Rat/Mouse/Canine/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 3 mg/mL |
| Purification: | Epitope affinity purified |
| Dilution Range: | WB:1:500-1:2, 000 |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Immunogen: | Purified recombinant peptide derived from within residues 140 aa to the N-terminus of human EWSR1 produced in E. coli |
| Immunogen Region: | N-Term |
| Immunogen Sequence: | MASTDYSTYSQAAAQQGYSA ASTDYSTYSQAAAQQGYSAY STDYSTYSQAAAQQGYSAYT TDYSTYSQAAAQQGYSAYTA DYSTYSQAAAQQGYSAYTAQ YSTYSQAAAQQGYSAYTAQP STYSQAAAQQGYSAYTAQPT |
| Specificity: | Detects endogenous levels of EWSR1 by Western blot in the whole cell lysates (HeLa, LS174T, H69, Jurkat, SHSY5Y, 3T3NIH, AtT20, etc.). |
| Background | Goat polyclonal antibody to EWSR1. EWSR1, or Ewing Sarcoma Breakpoint Region 1, encodes the EWS protein, a member of the FET (FUS, EWS, TAF15) family of RNA-binding proteins. These proteins are involved in various cellular processes, including gene transcription and RNA splicing. The EWS protein has a transcriptional activation domain that initiates gene transcription and an RNA-binding domain that attaches to RNA molecules. This dual functionality suggests a role in both transcription regulation and RNA processing. |
Information sourced from Uniprot.org
