• Flow cytometric analysis of Jurkat cells using ETS1 monoclonal antibody (green) and negative control (purple).
  • Immunohistochemistry analysis of paraffin-embedded human Colon, Adipocytes tissues with AEC staining using ETS1 monoclonal antibody.
  • Immunofluorescence analysis of NIH/3T3 cells using ETS1 monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye.
  • Western blot analysis using ETS1 monoclonal antibody against Jurkat (1) , HepG2 (2) and ETS1-hIgGFc transfected HEK293 (3) cell lysate.

Anti-ETS1 antibody [8A8] (STJ98057)

SKU:
STJ98057

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB/IHC/IF/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Protein C-ets-1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications.
Clonality: Monoclonal
Clone ID: 8A8
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ETS1
Gene ID: 2113
Uniprot ID: ETS1_HUMAN
Specificity: ETS1 Monoclonal Antibody detects endogenous levels of ETS1 protein.
Immunogen: Purified recombinant fragment of human ETS1 expressed in E. Coli.
Post Translational Modifications Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2.which inhibits transcriptional activity. Ubiquitinated.which induces proteasomal degradation. Phosphorylation at Ser-251, Ser-282 and Ser-285 by CaMK2/CaMKII in response to calcium signaling decreases affinity for DNA: an increasing number of phosphoserines causes DNA-binding to become progressively weaker.
Function Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. Isoform Ets-1 p27: Acts as a dominant-negative for isoform c-ETS-1A.
Protein Name Protein C-Ets-1
P54
Database Links Reactome: R-HSA-2559585
Cellular Localisation Nucleus
Cytoplasm
Delocalizes From Nucleus To Cytoplasm When Coexpressed With Isoform Ets-1 P27
Alternative Antibody Names Anti-Protein C-Ets-1 antibody
Anti-P54 antibody
Anti-ETS1 antibody
Anti-EWSR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance