Anti-ETBR antibody [SAA0780] (STJA0027690)

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STJA0027690
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Host: Mouse
Applications: ELISA/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Endothelin Receptor Type B is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0780
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: EDNRB
Gene ID: 1910
Uniprot ID: EDNRB_HUMAN
Post Translational Modifications Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405.
Function Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Name Endothelin Receptor Type B
Et-B
Et-Br
Endothelin Receptor Non-Selective Type
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-9856649
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalized After Activation By Endothelins
Alternative Antibody Names Anti-Endothelin Receptor Type B antibody
Anti-Et-B antibody
Anti-Et-Br antibody
Anti-Endothelin Receptor Non-Selective Type antibody
Anti-EDNRB antibody
Anti-ETRB antibody

Information sourced from Uniprot.org