Anti-ETBR antibody [hu5E9v1] (STJA0022270)

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STJA0022270
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Short Description :Human monoclonal Endothelin Receptor Type B antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA
Host:Human
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Clonality :Monoclonal
Clone ID :hu5E9v1
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Protein A/G purified from cell culture supernatant
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol:EDNRB
Gene ID:1910
Uniprot ID:EDNRB_HUMAN
Post Translational Modifications Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405.
Function Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Name Endothelin Receptor Type B
Et-B
Et-Br
Endothelin Receptor Non-Selective Type
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-9856649
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalized After Activation By Endothelins
Alternative Antibody Names Anti-Endothelin Receptor Type B antibody
Anti-Et-B antibody
Anti-Et-Br antibody
Anti-Endothelin Receptor Non-Selective Type antibody
Anti-EDNRB antibody
Anti-ETRB antibody

Information sourced from Uniprot.org