Anti-Estrogen Related Receptor gamma antibody [R09-2X1] (STJA0037351)

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STJA0037351
£133.50 - £281.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Estrogen Related Receptor gamma for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R09-2X1
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Purified
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: ESRRG
Gene ID: 2104
Uniprot ID: ERR3_HUMAN
Immunogen: A synthesized peptide derived from human ESRRG
Tissue Specificity Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
Post Translational Modifications Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
Function Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle.
Protein Name Estrogen-Related Receptor Gamma
Err Gamma-2
Estrogen Receptor-Related Protein 3
Nuclear Receptor Subfamily 3 Group B Member 3
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Estrogen-Related Receptor Gamma antibody
Anti-Err Gamma-2 antibody
Anti-Estrogen Receptor-Related Protein 3 antibody
Anti-Nuclear Receptor Subfamily 3 Group B Member 3 antibody
Anti-ESRRG antibody
Anti-ERR3 antibody
Anti-ERRG2 antibody
Anti-KIAA0832 antibody
Anti-NR3B3 antibody

Information sourced from Uniprot.org

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