Anti-ESCO2 antibody (STJA0008364)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ESCO2
General Information
| Short Description | Rabbit polyclonal anti-N-acetyltransferase ESCO2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ESCO2 |
| Gene ID | 157570 |
| Uniprot ID | ESCO2_HUMAN |
| Immunogen | Synthesized peptide derived from human ESCO2 |
| Specificity | This antibody detects endogenous levels of ESCO2 at Human, Mouse |
Additional Info
| Function | Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3. |
| Protein Name | N-Acetyltransferase Esco2Establishment Factor-Like Protein 2Efo2Efo2pHefo2Establishment Of Cohesion 1 Homolog 2Eco1 Homolog 2 |
| Database Links | Reactome: R-HSA-2468052 |
| Cellular Localisation | NucleusChromosomeNuclear In Interphase CellsExcluded From Chromosomes During Metaphase But Reassociates With Chromosomes In Telophase |
| Alternative Antibody Names | Anti-N-Acetyltransferase Esco2 antibodyAnti-Establishment Factor-Like Protein 2 antibodyAnti-Efo2 antibodyAnti-Efo2p antibodyAnti-Hefo2 antibodyAnti-Establishment Of Cohesion 1 Homolog 2 antibodyAnti-Eco1 Homolog 2 antibodyAnti-ESCO2 antibody |
Information sourced from Uniprot.org