Post Translational Modifications | Phosphorylated during mitosis, when associated with chromosomes. |
Function | Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3. |
Protein Name | N-Acetyltransferase Esco1Ctf7 Homolog 1Establishment Factor-Like Protein 1Efo1Efo1pHefo1Establishment Of Cohesion 1 Homolog 1Eco1 Homolog 1Eso1 Homolog 1 |
Database Links | Reactome: R-HSA-2468052 |
Cellular Localisation | NucleusChromosomeNuclear At InterphaseAssociated With Chromosomes During Mitosis |
Alternative Antibody Names | Anti-N-Acetyltransferase Esco1 antibodyAnti-Ctf7 Homolog 1 antibodyAnti-Establishment Factor-Like Protein 1 antibodyAnti-Efo1 antibodyAnti-Efo1p antibodyAnti-Hefo1 antibodyAnti-Establishment Of Cohesion 1 Homolog 1 antibodyAnti-Eco1 Homolog 1 antibodyAnti-Eso1 Homolog 1 antibodyAnti-ESCO1 antibodyAnti-EFO1 antibodyAnti-KIAA1911 antibody |
Information sourced from Uniprot.org