• Human colon adenocarcinoma stained with MOC-31 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of tumor cells.

Anti-ESA antibody [MOC‐31] (STJ180098)

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STJ180098

£152.50 - £510.50
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-ESA is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: MOC‐31
Conjugation: Unconjugated
Isotype: IgG1/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100‐200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: FLOT2
Gene ID: 2319
Uniprot ID: FLOT2_HUMAN
Specificity: Positive control: Colon carcinoma
Immunogen: Neuraminidase treated GLS-1 human small cell lung carcinoma cells
Tissue Specificity In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Post Translational Modifications ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells.
Function May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Protein Name Flotillin-2
Epidermal Surface Antigen
Esa
Membrane Component Chromosome 17 Surface Marker 1
Database Links Reactome: R-HSA-5213460
Reactome: R-HSA-5675482
Reactome: R-HSA-8849932
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Reactome: R-HSA-9696264
Reactome: R-HSA-9696273
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Membrane
Caveola
Endosome
Lipid-Anchor
Membrane-Associated Protein Of Caveolae
Alternative Antibody Names Anti-Flotillin-2 antibody
Anti-Epidermal Surface Antigen antibody
Anti-Esa antibody
Anti-Membrane Component Chromosome 17 Surface Marker 1 antibody
Anti-FLOT2 antibody
Anti-ESA1 antibody
Anti-M17S1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance