• Human kidney stained with anti-Erythropoietin antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tubular cells.

Anti-Erythropoietin antibody (28-162aa) [ZM135] (STJ180351)

SKU:
STJ180351

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Erythropoietin (28-162aa) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZM135
Conjugation: Unconjugated
Isotype: IgG1/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100‐200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: EPO
Gene ID: 2056
Uniprot ID: EPO_HUMAN
Immunogen Region: 28-162aa
Specificity: Positive control: Kidney
Immunogen: Recombinant fragment of human EPO protein (around aa 28-162)
Tissue Specificity Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
Function Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Protein Name Erythropoietin
Epoetin
Database Links Reactome: R-HSA-1234158
Reactome: R-HSA-9006335
Reactome: R-HSA-9027276
Reactome: R-HSA-9027277
Reactome: R-HSA-9027283
Reactome: R-HSA-9027284
Cellular Localisation Secreted
Alternative Antibody Names Anti-Erythropoietin antibody
Anti-Epoetin antibody
Anti-EPO antibody

Information sourced from Uniprot.org

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