Anti-ERVMER34-1 antibody (391-441 aa) (STJ193569)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MER34 at the amino acid range 391-441
General Information
| Short Description | Rabbit polyclonal anti-Endogenous retroviral envelope protein HEMO open reading frame (391-441 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ERVMER34-1 |
| Gene ID | 100288413 |
| Uniprot ID | MER34_HUMAN |
| Immunogen | Synthesized peptide derived from the human MER34 at the amino acid range 391-441 |
| Immunogen Region | 391-441 aa |
| Specificity | This antibody detects endogenous levels of MER34 at Human |
Additional Info
| Post Translational Modifications | N-glycosylated. Endogenous retroviral envelope protein HEMO: Cleaved by some metalloproteinase at 432-Gln-Arg-433 (mainly) or 433-Arg-Gln-434, leading to release the secreted form (Endogenous retroviral envelope protein HEMO, secreted form) in the extracellular medium. |
| Function | Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. |
| Protein Name | Endogenous Retroviral Envelope Protein HemoEndogenous Retrovirus Group Mer34 Member 1 Env PolyproteinHerv-Mer_4q12 Provirus Ancestral Env PolyproteinHuman Endogenous Mer34Medium-Reiteration-Frequency-Family-34 Open Reading FrameHuman Endogenous Mer34 OrfHemo Cleaved Into - Endogenous Retroviral Envelope Protein Hemo - Secreted FormEndogenous Retroviral Envelope Protein Hemo - 48 Kda Form |
| Database Links | |
| Cellular Localisation | Endogenous Retroviral Envelope Protein Hemo: Cell MembraneSingle-Pass Type I Membrane ProteinThis Uncleaved Form Present At The Cell Surface Represents The Major FormEndogenous Retroviral Envelope Protein HemoSecreted Form: SecretedThis Secreted FormWhich Is Released In The Extracellular Medium Following CleavageConstitutes A Minor Form |
| Alternative Antibody Names | Anti-Endogenous Retroviral Envelope Protein Hemo antibodyAnti-Endogenous Retrovirus Group Mer34 Member 1 Env Polyprotein antibodyAnti-Herv-Mer_4q12 Provirus Ancestral Env Polyprotein antibodyAnti-Human Endogenous Mer34 antibodyAnti-Medium-Reiteration-Frequency-Family-34 Open Reading Frame antibodyAnti-Human Endogenous Mer34 Orf antibodyAnti-Hemo Cleaved Into - Endogenous Retroviral Envelope Protein Hemo - Secreted Form antibodyAnti-Endogenous Retroviral Envelope Protein Hemo - 48 Kda Form antibodyAnti-ERVMER34-1 antibodyAnti-HEMO antibodyAnti-LP9056 antibody |
Information sourced from Uniprot.org