• Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
  • Western blot analysis of various cells using Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
  • Western blot analysis of HEPG2 3T3 Hela cells using ERLIN1/2 Polyclonal Antibody diluted at 1:800. Secondary antibody was diluted at 1:20000

Anti-ERLIN1/2 antibody (31-80 aa) (STJ98620)

SKU:
STJ98620

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Erlin-1 and Erlin-2 (31-80 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:10000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERLIN1
ERLIN2
Gene ID: 10613
11160
Uniprot ID: ERLN1_HUMAN
ERLN2_HUMAN
Immunogen Region: 31-80 aa
Specificity: ERLIN1/2 Polyclonal Antibody detects endogenous levels of ERLIN1/2
Immunogen: Synthesized peptide derived from ERLIN1/2 at the amino acid range 31-80
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex. (Microbial infection) Required early in hepatitis C virus (HCV) infection to initiate RNA replication, and later in the infection to support infectious virus production.
Protein Name Erlin-1
Endoplasmic Reticulum Lipid Raft-Associated Protein 1
Protein Ke04
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1
Spfh Domain-Containing Protein 1
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5678895
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Erlin-1 antibody
Anti-Endoplasmic Reticulum Lipid Raft-Associated Protein 1 antibody
Anti-Protein Ke04 antibody
Anti-Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1 antibody
Anti-Spfh Domain-Containing Protein 1 antibody
Anti-ERLIN1 antibody
Anti-C10orf69 antibody
Anti-KE04 antibody
Anti-KEO4 antibody
Anti-SPFH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance