Anti-EPS8L2 antibody (1-50 aa) (STJ92964)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ES8L2 at the amino acid range 1-50
General Information
| Short Description | Rabbit polyclonal anti-Epidermal growth factor receptor kinase substrate 8-like protein 2 (1-50 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPS8L2 |
| Gene ID | 64787 |
| Uniprot ID | ES8L2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ES8L2 at the amino acid range 1-50 |
| Immunogen Region | 1-50 aa |
| Specificity | Eps8L2 Polyclonal Antibody detects endogenous levels of Eps8L2 protein. |
Additional Info
| Function | Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells. |
| Protein Name | Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 2Eps8-Like Protein 2Epidermal Growth Factor Receptor Pathway Substrate 8-Related Protein 2Eps8-Related Protein 2 |
| Database Links | Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCell ProjectionStereociliumLocalizes At The Tips Of The Stereocilia Of The Inner And Outer Hair Cells |
| Alternative Antibody Names | Anti-Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 2 antibodyAnti-Eps8-Like Protein 2 antibodyAnti-Epidermal Growth Factor Receptor Pathway Substrate 8-Related Protein 2 antibodyAnti-Eps8-Related Protein 2 antibodyAnti-EPS8L2 antibodyAnti-EPS8R2 antibodyAnti-PP13181 antibody |
Information sourced from Uniprot.org