| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Epidermal growth factor receptor kinase substrate 8-like protein 2 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EPS8L2 |
| Gene ID: | 64787 |
| Uniprot ID: | ES8L2_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | Eps8L2 Polyclonal Antibody detects endogenous levels of Eps8L2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ES8L2 at the amino acid range 1-50 |
| Function | Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells. |
| Protein Name | Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 2Eps8-Like Protein 2Epidermal Growth Factor Receptor Pathway Substrate 8-Related Protein 2Eps8-Related Protein 2 |
| Database Links | Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCell ProjectionStereociliumLocalizes At The Tips Of The Stereocilia Of The Inner And Outer Hair Cells |
| Alternative Antibody Names | Anti-Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 2 antibodyAnti-Eps8-Like Protein 2 antibodyAnti-Epidermal Growth Factor Receptor Pathway Substrate 8-Related Protein 2 antibodyAnti-Eps8-Related Protein 2 antibodyAnti-EPS8L2 antibodyAnti-EPS8R2 antibodyAnti-PP13181 antibody |
Information sourced from Uniprot.org
