| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | EPO |
| Gene ID: | 2056 |
| Uniprot ID: | EPO_HUMAN |
| Immunogen Region: | 28-193 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-193 of EPO (NP_000790.2). |
| Immunogen Sequence: | APPRLICDSRVLERYLLEAK EAENITTGCAEHCSLNENIT VPDTKVNFYAWKRMEVGQQA VEVWQGLALLSEAVLRGQAL LVNSSQPWEPLQLHVDKAVS GLRSLTTLLRALGAQKEAIS PPDAASAAPLRTITADTFRK LFRVYSNFLRGKLKLYTGEA CRTGDR |
| Tissue Specificity | Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. |
| Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
| Protein Name | ErythropoietinEpoetin |
| Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-9006335Reactome: R-HSA-9027276Reactome: R-HSA-9027277Reactome: R-HSA-9027283Reactome: R-HSA-9027284 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Erythropoietin antibodyAnti-Epoetin antibodyAnti-EPO antibody |
Information sourced from Uniprot.org
