• Western blot analysis of lysates from COLO, 293, and HeLa cells, using EPHB6 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HeLa cells, using EPHB6 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHB6 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using EphB6 Polyclonal Antibody

Anti-EPHB6 antibody (861-910 aa) (STJ92953)

SKU:
STJ92953

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ephrin type-B receptor 6 (861-910 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EPHB6
Gene ID: 2051
Uniprot ID: EPHB6_HUMAN
Immunogen Region: 861-910 aa
Specificity: EphB6 Polyclonal Antibody detects endogenous levels of EphB6 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human EPHB6 at the amino acid range 861-910
Post Translational Modifications Ligand-binding increases phosphorylation on tyrosine residues. Phosphorylation on tyrosine residues is mediated by transphosphorylation by the catalytically active EPHB1 in a ligand-independent manner. Tyrosine phosphorylation of the receptor may act as a switch on the functional transition from cell adhesion/attraction to de-adhesion/repulsion.
Function Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.
Protein Name Ephrin Type-B Receptor 6
Hep
Tyrosine-Protein Kinase-Defective Receptor Eph-6
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928662
Reactome: R-HSA-3928664
Reactome: R-HSA-3928665
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Secreted
Alternative Antibody Names Anti-Ephrin Type-B Receptor 6 antibody
Anti-Hep antibody
Anti-Tyrosine-Protein Kinase-Defective Receptor Eph-6 antibody
Anti-EPHB6 antibody

Information sourced from Uniprot.org

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