Host: |
Rabbit |
Applications: |
CM/ELISA/ICC/IF/IHC/IP/WB |
Reactivity: |
Horse/Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-EPAC2 (743-762) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
FITC |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.67 µg/µl |
Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
Rapgef4Uniprot ID=RPGF4_RAT" |
Immunogen Region: |
743-762 |
Specificity: |
Does not cross react with other Epac family proteins. |
Immunogen: |
Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein. |
Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2. |
Protein Name | Rap Guanine Nucleotide Exchange Factor 4Exchange Factor Directly Activated By Camp 2Exchange Protein Directly Activated By Camp 2Epac 2Camp-Regulated Guanine Nucleotide Exchange Factor IiCamp-Gefii |
Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Rap Guanine Nucleotide Exchange Factor 4 antibodyAnti-Exchange Factor Directly Activated By Camp 2 antibodyAnti-Exchange Protein Directly Activated By Camp 2 antibodyAnti-Epac 2 antibodyAnti-Camp-Regulated Guanine Nucleotide Exchange Factor Ii antibodyAnti-Camp-Gefii antibodyAnti-Rapgef4 antibodyAnti-Cgef2 antibodyAnti-Epac2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance