| Host: | Rabbit |
| Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Horse/Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-EPAC2 (743-762) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.67 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Rapgef4 |
| Uniprot ID: | RPGF4_RAT |
| Immunogen Region: | 743-762 |
| Specificity: | Does not cross react with other Epac family proteins. |
| Immunogen: | Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein. |
| Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2. |
| Protein Name | Rap Guanine Nucleotide Exchange Factor 4Exchange Factor Directly Activated By Camp 2Exchange Protein Directly Activated By Camp 2Epac 2Camp-Regulated Guanine Nucleotide Exchange Factor IiCamp-Gefii |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rap Guanine Nucleotide Exchange Factor 4 antibodyAnti-Exchange Factor Directly Activated By Camp 2 antibodyAnti-Exchange Protein Directly Activated By Camp 2 antibodyAnti-Epac 2 antibodyAnti-Camp-Regulated Guanine Nucleotide Exchange Factor Ii antibodyAnti-Camp-Gefii antibodyAnti-Rapgef4 antibodyAnti-Cgef2 antibodyAnti-Epac2 antibody |
Information sourced from Uniprot.org
