Anti-EP4 prostaglandin receptor antibody (Internal) (STJ70869)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-EP4 prostaglandin receptor (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 55kDa band observed in Human Testes lysates (calculated MW of 53.1kDa according to NP_000949.1). Recommended concentration: 0.1-0.3ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PTGER4 |
| Gene ID | 5734 |
| Uniprot ID | PE2R4_HUMAN |
| Accession Number | NP_000949.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | LEREVSKNPDLQA |
Additional Info
| Post Translational Modifications | Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
| Protein Name | Prostaglandin E2 Receptor Ep4 SubtypePge Receptor Ep4 SubtypePge2 Receptor Ep4 SubtypeProstanoid Ep4 Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep4 Subtype antibodyAnti-Pge Receptor Ep4 Subtype antibodyAnti-Pge2 Receptor Ep4 Subtype antibodyAnti-Prostanoid Ep4 Receptor antibodyAnti-PTGER4 antibodyAnti-PTGER2 antibody |
Information sourced from Uniprot.org