Anti-ENTREP1 antibody (STJA0009126)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C9orf61
General Information
| Short Description | Rabbit polyclonal anti-Endosomal transmembrane epsin interactor 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENTREP1 |
| Gene ID | 9413 |
| Uniprot ID | EREP1_HUMAN |
| Immunogen | Synthesized peptide derived from human C9orf61 |
| Specificity | This antibody detects endogenous levels of C9orf61 at Human, Mouse |
Additional Info
| Post Translational Modifications | Monoubiquitinated at Lys-274, Lys-329 and Lys-365 by ITCH. |
| Function | Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway. |
| Protein Name | Endosomal Transmembrane Epsin Interactor 1Endosomal Transmembrane Binding With Epsin |
| Database Links | |
| Cellular Localisation | Early Endosome MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneRecycling Endosome MembraneCell MembraneEnriched In Endosomes Compared To The Cell Membrane |
| Alternative Antibody Names | Anti-Endosomal Transmembrane Epsin Interactor 1 antibodyAnti-Endosomal Transmembrane Binding With Epsin antibodyAnti-ENTREP1 antibodyAnti-C9orf61 antibodyAnti-FAM189A2 antibodyAnti-X123 antibody |
Information sourced from Uniprot.org