| Function | Isoform 1: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner, with a preference for pyrimidines. Preferentially hydrolyzes UTP and TTP. AMP, ADP, ATP and UMP are not substrates. Preferentially activated by Ca(2+) over Mg(2+). Isoform 2: Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP). Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP. Can use either Ca(2+) or Mg(2+) equally. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 4Ntpdase 4Golgi UdpaseLysosomal Apyrase-Like Protein Of 70 KdaUridine-DiphosphataseUdpase |
| Database Links | Reactome: R-HSA-8850843 |
| Cellular Localisation | Isoform 1: Cytoplasmic VesicleAutophagosome MembraneMulti-Pass Membrane ProteinLysosome MembraneIsoform 2: Golgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 4 antibodyAnti-Ntpdase 4 antibodyAnti-Golgi Udpase antibodyAnti-Lysosomal Apyrase-Like Protein Of 70 Kda antibodyAnti-Uridine-Diphosphatase antibodyAnti-Udpase antibodyAnti-ENTPD4 antibodyAnti-KIAA0392 antibodyAnti-LALP70 antibodyAnti-LYSAL1 antibody |
Information sourced from Uniprot.org
