Anti-ENT1 antibody (410-460) {Biotin} (STJ500883)

SKU:
STJ500883-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ENT1 (410-460) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Slc29a1
Gene ID: 63959
Uniprot ID: S29A1_MOUSE
Immunogen Region: 410-460
Immunogen: Synthetic peptide taken within amino acid reigon 410-460 on mouse Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1 protein.
Tissue Specificity Highly expressed in heart, spleen, lung, liver and testis. Lower level of expression in brain and kidney. Expressed in adipose tissues, brown adipocytes expressing significantly higher amounts than white adipocytes. Expressed in seminiferous tubules.
Post Translational Modifications Glycosylated.
Function Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure.
Protein Name Equilibrative Nucleoside Transporter 1
Ment1
Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter
Equilibrative Nbmpr-Sensitive Nucleoside Transporter
Nucleoside Transporter - Es-Type
Solute Carrier Family 29 Member 1
Database Links Reactome: R-MMU-83936
Reactome: -MMU-9748787
Reactome: -MMU-9755088
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Cell Membrane
Alternative Antibody Names Anti-Equilibrative Nucleoside Transporter 1 antibody
Anti-Ment1 antibody
Anti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibody
Anti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibody
Anti-Nucleoside Transporter - Es-Type antibody
Anti-Solute Carrier Family 29 Member 1 antibody
Anti-Slc29a1 antibody
Anti-Ent1 antibody

Information sourced from Uniprot.org

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