| Host: | Rabbit |
| Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-ENSG00000285188 (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.65 µg/µl |
| Dilution Range: | WB: 1:500-1:2, 500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | PDE4C |
| Gene ID: | 5143 |
| Uniprot ID: | PDE4C_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | This antibody detects 3 isoforms of PDE4C subclasses: PDE4C1, PDE4C2, and PDE4C3. |
| Immunogen: | Synthetic cyclic carboxy-terminal peptide common to all PDE4C variants. |
| Tissue Specificity | Expressed in various tissues but not in cells of the immune system. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
| Protein Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4cDpde1Pde21Camp-Specific Phosphodiesterase 4c |
| Database Links | Reactome: R-HSA-180024Reactome: R-HSA-418555 |
| Cellular Localisation | Cell ProjectionCilium |
| Alternative Antibody Names | Anti-3' -5'-Cyclic-Amp Phosphodiesterase 4c antibodyAnti-Dpde1 antibodyAnti-Pde21 antibodyAnti-Camp-Specific Phosphodiesterase 4c antibodyAnti-PDE4C antibodyAnti-DPDE1 antibody |
Information sourced from Uniprot.org