Host: | Rabbit |
Applications: | WB/IF/ICC/IP/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ENO2 |
Gene ID: | 2026 |
Uniprot ID: | ENOG_HUMAN |
Immunogen Region: | 195-434 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 195-434 of human ENO2 (NP_001966.1). |
Immunogen Sequence: | VIKDKYGKDATNVGDEGGFA PNILENSEALELVKEAIDKA GYTEKIVIGMDVAASEFYRD GKYDLDFKSPTDPSRYITGD QLGALYQDFVRDYPVVSIED PFDQDDWAAWSKFTANVGIQ IVGDDLTVTNPKRIERAVEE KACNCLLLKVNQIGSVTEAI QACKLAQENGWGVMVSHRSG ETEDTFIADLVVGLCTGQIK TGAPCRSERLAKYNQLMRIE EELGDEARFAGHNFRNPSV |
Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
Protein Name | Gamma-Enolase2-Phospho-D-Glycerate Hydro-LyaseEnolase 2Neural EnolaseNeuron-Specific EnolaseNse |
Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
Cellular Localisation | CytoplasmCell MembraneCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
Alternative Antibody Names | Anti-Gamma-Enolase antibodyAnti-2-Phospho-D-Glycerate Hydro-Lyase antibodyAnti-Enolase 2 antibodyAnti-Neural Enolase antibodyAnti-Neuron-Specific Enolase antibodyAnti-Nse antibodyAnti-ENO2 antibody |
Information sourced from Uniprot.org