Anti-Endomucin antibody (212-261 aa) [SRM5423] (STJ11107336)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Endomucin (212-261 aa) antibody for use in IHC-P and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5423 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EMCN |
| Gene ID | 51705 |
| Uniprot ID | MUCEN_HUMAN |
| Immunogen Region | 212-261 aa |
| Immunogen Sequence | LYRMCWKADPGTPENGNDQP QSDKESVKLLTVKTISHESG EHSAQGKTKN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 212-261 of human Endomucin (NP_057326.2). |
Additional Info
| Tissue Specificity | Expressed in heart, kidney and lung. |
| Post Translational Modifications | Highly O-glycosylated. Sialic acid-rich glycoprotein. |
| Function | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
| Protein Name | EndomucinEndomucin-2Gastric Cancer Antigen Ga34Mucin-14Muc-14 |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinMembraneConsistently Localized To The Plasma Membrane And Less Abundantly To Golgi-Like Perinuclear StacksIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Endomucin antibodyAnti-Endomucin-2 antibodyAnti-Gastric Cancer Antigen Ga34 antibodyAnti-Mucin-14 antibodyAnti-Muc-14 antibodyAnti-EMCN antibodyAnti-EMCN2 antibodyAnti-MUC14 antibody |
Information sourced from Uniprot.org