| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EMCN |
| Gene ID: | 51705 |
| Uniprot ID: | MUCEN_HUMAN |
| Immunogen Region: | 19-135 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-135 of human Endomucin (NP_057326.2). |
| Immunogen Sequence: | NSTGVLEAANNSLVVTTTKP SITTPNTESLQKNVVTPTTG TTPKGTITNELLKMSLMSTA TFLTSKDEGLKATTTDVRKN DSIISNVTVTSVTLPNAVST LQSSKPKTETQSSIKTT |
| Tissue Specificity | Expressed in heart, kidney and lung. |
| Post Translational Modifications | Highly O-glycosylated. Sialic acid-rich glycoprotein. |
| Function | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
| Protein Name | EndomucinEndomucin-2Gastric Cancer Antigen Ga34Mucin-14Muc-14 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinMembraneConsistently Localized To The Plasma Membrane And Less Abundantly To Golgi-Like Perinuclear StacksIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Endomucin antibodyAnti-Endomucin-2 antibodyAnti-Gastric Cancer Antigen Ga34 antibodyAnti-Mucin-14 antibodyAnti-Muc-14 antibodyAnti-EMCN antibodyAnti-EMCN2 antibodyAnti-MUC14 antibody |
Information sourced from Uniprot.org