| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Elongation of very long chain fatty acids protein 6 (21-70 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELOVL6 |
| Gene ID: | 79071 |
| Uniprot ID: | ELOV6_HUMAN |
| Immunogen Region: | 21-70 aa |
| Specificity: | ELOVL6 Polyclonal Antibody detects endogenous levels of ELOVL6 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ELOVL6 at the amino acid range 21-70 |
| Post Translational Modifications | N-Glycosylated. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 6 3-Keto Acyl-Coa Synthase Elovl6 Elovl Fatty Acid Elongase 6 Elovl Fa Elongase 6 Elongation Of Very Long Chain Fatty Acids Protein 6 Fatty Acid Elongase 2 Helo2 Fatty Acyl-Coa Elongase Long-Chain Fatty-Acyl Elongase Very Long Chain 3-Ketoacyl-Coa Synthase 6 Very Long Chain 3-Oxoacyl-Coa Synthase 6 |
| Database Links | Reactome: R-HSA-2426168 Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 6 antibody Anti-3-Keto Acyl-Coa Synthase Elovl6 antibody Anti-Elovl Fatty Acid Elongase 6 antibody Anti-Elovl Fa Elongase 6 antibody Anti-Elongation Of Very Long Chain Fatty Acids Protein 6 antibody Anti-Fatty Acid Elongase 2 antibody Anti-Helo2 antibody Anti-Fatty Acyl-Coa Elongase antibody Anti-Long-Chain Fatty-Acyl Elongase antibody Anti-Very Long Chain 3-Ketoacyl-Coa Synthase 6 antibody Anti-Very Long Chain 3-Oxoacyl-Coa Synthase 6 antibody Anti-ELOVL6 antibody Anti-FACE antibody Anti-LCE antibody |
Information sourced from Uniprot.org
