Anti-ELOVL1 antibody (101-150 aa) (STJ92900)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ELOVL1 at the amino acid range 101-150
General Information
| Short Description | Rabbit polyclonal anti-Elongation of very long chain fatty acids protein 1 (101-150 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELOVL1 |
| Gene ID | 64834 |
| Uniprot ID | ELOV1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ELOVL1 at the amino acid range 101-150 |
| Immunogen Region | 101-150 aa |
| Specificity | ELOVL1 Polyclonal Antibody detects endogenous levels of ELOVL1 protein. |
Additional Info
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. |
| Protein Name | Very Long Chain Fatty Acid Elongase 13-Keto Acyl-Coa Synthase Elovl1Elovl Fatty Acid Elongase 1Elovl Fa Elongase 1Elongation Of Very Long Chain Fatty Acids Protein 1Very Long Chain 3-Ketoacyl-Coa Synthase 1Very Long Chain 3-Oxoacyl-Coa Synthase 1 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 1 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl1 antibodyAnti-Elovl Fatty Acid Elongase 1 antibodyAnti-Elovl Fa Elongase 1 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 1 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 1 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 1 antibodyAnti-ELOVL1 antibodyAnti-SSC1 antibodyAnti-CGI-88 antibody |
Information sourced from Uniprot.org