| Short Description : | Goat polyclonal ELAVL1 (C-Term) antibody for use in WB in human, rat, mouse, canine and monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Goat |
| Reactivity: | Human/Rat/Mouse/Canine/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 3 mg/mL |
| Purification: | Epitope affinity purified |
| Dilution Range: | WB:1:500-1:5, 000 |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Immunogen: | Purified recombinant peptide derived from within residues 271 aa to the C-terminus of human ELAVL1 produced in E. coli. |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | MTNVKVIRDFNTNKCKGFGF TNVKVIRDFNTNKCKGFGFV NVKVIRDFNTNKCKGFGFVT |
| Specificity: | Detects endogenous levels of ELAVL1 by Western blot in the whole cell lysates (H69, HeLa, MCF7, AtT20, LS174T, 293HEK, IMCD3, Jurkat, COS7, SHSY5Y, NIH3T3, etc.). |
| Background | Goat polyclonal antibody to ELAVL1. ELAVL1, also known as HuR (Human antigen R) , is a ubiquitously expressed RNA-binding protein that plays a pivotal role in post-transcriptional regulation of gene expression. It belongs to the ELAV (embryonic lethal abnormal vision) family of proteins, which are characterized by their ability to bind to AU-rich elements (AREs) in the 3 untranslated regions (3 UTRs) of target mRNAs, thereby influencing mRNA stability and translation. |
Information sourced from Uniprot.org

