| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc phosphodiesterase ELAC protein 1 (126-176 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELAC1 |
| Gene ID: | 55520 |
| Uniprot ID: | RNZ1_HUMAN |
| Immunogen Region: | 126-176 aa |
| Specificity: | This antibody detects endogenous levels of human RNZ1 |
| Immunogen: | Synthesized peptide derived from the human RNZ1 at the amino acid range 126-176 |
| Function | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1. |
| Protein Name | Zinc Phosphodiesterase Elac Protein 1Deleted In Ma29Elac Homolog Protein 1Ribonuclease Z 1Rnase Z 1Trna 3 Endonuclease 1Trnase Z 1 |
| Cellular Localisation | CytoplasmCytosolNucleusMainly Cytosolic |
| Alternative Antibody Names | Anti-Zinc Phosphodiesterase Elac Protein 1 antibodyAnti-Deleted In Ma29 antibodyAnti-Elac Homolog Protein 1 antibodyAnti-Ribonuclease Z 1 antibodyAnti-Rnase Z 1 antibodyAnti-Trna 3 Endonuclease 1 antibodyAnti-Trnase Z 1 antibodyAnti-ELAC1 antibodyAnti-D29 antibody |
Information sourced from Uniprot.org
