Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. |
Protein Name | Ephrin-A4Eph-Related Receptor Tyrosine Kinase Ligand 4Lerk-4 |
Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
Alternative Antibody Names | Anti-Ephrin-A4 antibodyAnti-Eph-Related Receptor Tyrosine Kinase Ligand 4 antibodyAnti-Lerk-4 antibodyAnti-EFNA4 antibodyAnti-EPLG4 antibodyAnti-LERK4 antibody |
Information sourced from Uniprot.org