| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-EF-hand domain-containing protein 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EFHC1 |
| Gene ID: | 114327 |
| Uniprot ID: | EFHC1_HUMAN |
| Specificity: | This antibody detects endogenous levels of EFHC1 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human EFHC1 |
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. |
| Protein Name | Ef-Hand Domain-Containing Protein 1Myoclonin-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeFlagellum AxonemeMicrotubule Organizing CenterCentrosomeSpindleSpindle Pole |
| Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein 1 antibodyAnti-Myoclonin-1 antibodyAnti-EFHC1 antibody |
Information sourced from Uniprot.org
