| Host: | Human |
| Applications: | Blocking/ELISA/FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Human monoclonal antibody anti-Endothelin-1 Receptor is suitable for use in Universaling, ELISA and Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SAA0802 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 0.01M PBS, pH 7.4, 0.09% Sodium azide. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Concentration: | 1 mg/ml |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | EDNRA |
| Gene ID: | 1909 |
| Uniprot ID: | EDNRA_HUMAN |
| Function | Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
| Protein Name | Endothelin-1 ReceptorEndothelin Receptor Type AEt-AEta-RHet-Ar |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Endothelin-1 Receptor antibodyAnti-Endothelin Receptor Type A antibodyAnti-Et-A antibodyAnti-Eta-R antibodyAnti-Het-Ar antibodyAnti-EDNRA antibodyAnti-ETA antibodyAnti-ETRA antibody |
Information sourced from Uniprot.org