| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Endothelin-1 receptor (378-427 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EDNRA |
| Gene ID: | 1909 |
| Uniprot ID: | EDNRA_HUMAN |
| Immunogen Region: | 378-427 aa |
| Specificity: | ETAR Polyclonal Antibody detects endogenous levels of ETAR protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human EDNRA at the amino acid range 378-427 |
| Function | Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
| Protein Name | Endothelin-1 ReceptorEndothelin Receptor Type AEt-AEta-RHet-Ar |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Endothelin-1 Receptor antibodyAnti-Endothelin Receptor Type A antibodyAnti-Et-A antibodyAnti-Eta-R antibodyAnti-Het-Ar antibodyAnti-EDNRA antibodyAnti-ETA antibodyAnti-ETRA antibody |
Information sourced from Uniprot.org