| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | EDA2R |
| Gene ID: | 60401 |
| Uniprot ID: | TNR27_HUMAN |
| Immunogen Region: | 1-138 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human EDA2R (NP_068555.1). |
| Immunogen Sequence: | MDCQENEYWDQWGRCVTCQR CGPGQELSKDCGYGEGGDAY CTACPPRRYKSSWGHHRCQS CITCAVINRVQKVNCTATSN AVCGDCLPRFYRKTRIGGLQ DQECIPCTKQTPTSEVQCAF QLSLVEADAPTVPPQEAT |
| Function | Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 27X-Linked Ectodysplasin-A2 ReceptorEda-A2 Receptor |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 27 antibodyAnti-X-Linked Ectodysplasin-A2 Receptor antibodyAnti-Eda-A2 Receptor antibodyAnti-EDA2R antibodyAnti-TNFRSF27 antibodyAnti-XEDAR antibodyAnti-UNQ2448 antibodyAnti-PRO5727 antibodyAnti-PRO34080 antibody |
Information sourced from Uniprot.org