| Function | Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. Isoform TAA binds only to the receptor EDAR, while isoform TA-A2 binds exclusively to the receptor EDA2R. May also play a role in cell adhesion. Isoform TAA binds only to the receptor EDAR, while isoform TA-A2 binds exclusively to the receptor EDA2R. Isoform TA-A2 binds exclusively to the receptor EDA2R. |
| Protein Name | Ectodysplasin-AEda Protein HomologTabby Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form |
| Database Links | Reactome: R-MMU-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinEctodysplasin-ASecreted Form: Secreted |
| Alternative Antibody Names | Anti-Ectodysplasin-A antibodyAnti-Eda Protein Homolog antibodyAnti-Tabby Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form antibodyAnti-Eda antibodyAnti-Ed1 antibodyAnti-Ta antibody |
Information sourced from Uniprot.org
