Anti-EDA1 antibody [Fs0331] (STJA0032135)

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STJA0032135-100
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Host: Mouse
Applications: ELISA/FCM/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-EDA1 for use in ELISA, FCM and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : Fs0331
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Endotoxin: Please contact us for this information.
Gene Symbol: EDA
Gene ID: 1896
Uniprot ID: EDA_HUMAN
Post Translational Modifications N-glycosylated. Processing by furin produces a secreted form.
Function Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. May also play a role in cell adhesion. Isoform 1: Binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor EDA2R. Isoform 3: Binds only to the receptor EDA2R.
Protein Name Ectodysplasin-A
Ectodermal Dysplasia Protein
Eda Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form
Database Links Reactome: R-HSA-5669034 Q92838-3
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Ectodysplasin-A
Secreted Form: Secreted
Alternative Antibody Names Anti-Ectodysplasin-A antibody
Anti-Ectodermal Dysplasia Protein antibody
Anti-Eda Protein Cleaved Into - Ectodysplasin-A - Membrane Form - Ectodysplasin-A - Secreted Form antibody
Anti-EDA antibody
Anti-ED1 antibody
Anti-EDA2 antibody

Information sourced from Uniprot.org

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