| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Augurin (41-90 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ECRG4 |
| Gene ID: | 84417 |
| Uniprot ID: | AUGN_HUMAN |
| Immunogen Region: | 41-90 aa |
| Specificity: | ECRG4 Polyclonal Antibody detects endogenous levels of ECRG4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ECRG4 at the amino acid range 41-90 |
| Function | Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. |
| Protein Name | AugurinEsophageal Cancer-Related Gene 4 ProteinEcrg4 |
| Cellular Localisation | SecretedCytoplasmApical Cell Membrane |
| Alternative Antibody Names | Anti-Augurin antibodyAnti-Esophageal Cancer-Related Gene 4 Protein antibodyAnti-Ecrg4 antibodyAnti-ECRG4 antibodyAnti-C2orf40 antibodyAnti-UNQ761 antibodyAnti-PRO1508 antibody |
Information sourced from Uniprot.org