| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | EBV |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-EBV-LMP is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | CS1-4 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Specificity: | Positive control: EBV positive cells |
| Immunogen: | Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP |
| Background | CS1-4 reacts strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. It also reacts with 25 to 50 per cent of EBV-associated undifferentiated nasopharyngeal carcinomas and with Reed Sternberg cells in approximately 90% of EBV-associated Hodgkin s lymphoma cases. The cocktail recognizes distinct epitopes on the hydrophilic carboxyl region of LMP which is exposed to the cytosol. |
Information sourced from Uniprot.org