Anti-Dystrophin antibody (200-250) (STJ507807)

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STJ507807-100
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Short Description :Rabbit polyclonal antibody anti-Dystrophin (200-250) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Applications:ELISA/IP/WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Formulation:Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:DMD
Gene ID:1756
Uniprot ID:DMD_HUMAN
Immunogen:Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytryptamine receptor 1A protein.
Immunogen Region:200-250
Function Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Protein Name Dystrophin
Database Links Reactome: R-HSA-3000171
Reactome: R-HSA-390522
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Postsynaptic Cell Membrane
In Muscle Cells
Sarcolemma Localization Requires The Presence Of Ank2
While Localization To Costameres Requires The Presence Of Ank3
Localizes To Neuromuscular Junctions (Nmjs)
In Adult Muscle
Nmj Localization Depends Upon Ank2 Presence
But Not In Newborn Animals
Alternative Antibody Names Anti-Dystrophin antibody
Anti-DMD antibody

Information sourced from Uniprot.org

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