Tissue Specificity | Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach. |
Function | Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14). |
Protein Name | Dual Specificity Protein Phosphatase 23Low Molecular Mass Dual Specificity Phosphatase 3Ldp-3Vh1-Like Phosphatase Z |
Cellular Localisation | CytoplasmCytosolNucleusMainly CytosolicAlso Nuclear |
Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 23 antibodyAnti-Low Molecular Mass Dual Specificity Phosphatase 3 antibodyAnti-Ldp-3 antibodyAnti-Vh1-Like Phosphatase Z antibodyAnti-DUSP23 antibodyAnti-LDP3 antibodyAnti-VHZ antibody |
Information sourced from Uniprot.org