| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DUSP14 |
| Gene ID: | 11072 |
| Uniprot ID: | DUS14_HUMAN |
| Immunogen Region: | 1-198 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DUSP14 (NP_008957.1). |
| Immunogen Sequence: | MSSRGHSTLPRTLMAPRMIS EGDIGGIAQITSSLFLGRGS VASNRHLLQARGITCIVNAT IEIPNFNWPQFEYVKVPLAD MPHAPIGLYFDTVADKIHSV SRKHGATLVHCAAGVSRSAT LCIAYLMKFHNVCLLEAYNW VKARRPVIRPNVGFWRQLID YERQLFGKSTVKMVQTPYGI VPDVYEKESRHLMPYWGI |
| Function | Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases. Plays a negative role in TCR signaling by dephosphorylating MAP3K7 adapter TAB1 leading to its inactivation. |
| Protein Name | Dual Specificity Protein Phosphatase 14Mkp-1-Like Protein Tyrosine PhosphataseMkp-LMitogen-Activated Protein Kinase Phosphatase 6Map Kinase Phosphatase 6Mkp-6 |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 14 antibodyAnti-Mkp-1-Like Protein Tyrosine Phosphatase antibodyAnti-Mkp-L antibodyAnti-Mitogen-Activated Protein Kinase Phosphatase 6 antibodyAnti-Map Kinase Phosphatase 6 antibodyAnti-Mkp-6 antibodyAnti-DUSP14 antibodyAnti-MKP6 antibody |
Information sourced from Uniprot.org