| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-D-aminoacyl-tRNA deacylase 1 deacylase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DTD1 |
| Gene ID: |
92675 |
| Uniprot ID: |
DTD1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of DTD1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human DTD1 |
| Post Translational Modifications | Preferentially phosphorylated in cells arrested early in S phase. Phosphorylation in the C-terminus weakens the interaction with CDC45. |
| Function | Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes. An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis.rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality. |
| Protein Name | D-Aminoacyl-Trna Deacylase 1DtdDna-Unwinding Element-Binding Protein BDue-BGly-Trna(Ala DeacylaseHistidyl-Trna Synthase-Related |
| Cellular Localisation | NucleusCytoplasmAssociated With Chromatin At Some Replication Origins Containing Functional Dna-Unwinding Elements |
| Alternative Antibody Names | Anti-D-Aminoacyl-Trna Deacylase 1 antibodyAnti-Dtd antibodyAnti-Dna-Unwinding Element-Binding Protein B antibodyAnti-Due-B antibodyAnti-Gly-Trna(Ala Deacylase antibodyAnti-Histidyl-Trna Synthase-Related antibodyAnti-DTD1 antibodyAnti-C20orf88 antibodyAnti-DUEB antibodyAnti-HARS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
