| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSTN |
| Gene ID: | 11034 |
| Uniprot ID: | DEST_HUMAN |
| Immunogen Region: | 1-165 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human Destrin (NP_006861.1). |
| Immunogen Sequence: | MASGVQVADEVCRIFYDMKV RKCSTPEEIKKRKKAVIFCL SADKKCIIVEEGKEILVGDV GVTITDPFKHFVGMLPEKDC RYALYDASFETKESRKEELM FFLWAPELAPLKSKMIYASS KDAIKKKFQGIKHECQANGP EDLNRACIAEKLGGSLIVAF EGCPV |
| Tissue Specificity | Widely distributed in various tissues. |
| Post Translational Modifications | ISGylated. |
| Function | Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner. |
| Protein Name | DestrinActin-Depolymerizing FactorAdf |
| Alternative Antibody Names | Anti-Destrin antibodyAnti-Actin-Depolymerizing Factor antibodyAnti-Adf antibodyAnti-DSTN antibodyAnti-ACTDP antibodyAnti-DSN antibody |
Information sourced from Uniprot.org